The St Kilda Football Club, nicknamed the Saints, is an Australian rules football club based in Melbourne, Victoria. The club plays in the Australian Football League (AFL), the sport's premier league.

The club's name originates from its original home base in the bayside Melbourne suburb of St Kilda in which the club was established in 1873. The club also has strong links to the south-eastern suburb of Moorabbin, due to its long-standing usage of their facilities.

St Kilda were one of five foundation teams of the Victorian Football Association (VFA), now known as the Victorian Football League (VFL), and later became one of eight foundation teams of the original Victorian Football League in 1897, now known as the AFL. Additionally, St Kilda are in an alignment with the Sandringham Football Club in the modern VFL.